Transition metal-catalyzed asymmetric carbon-carbon bond-forming reactions are essential in modern organic synthesis. Chiral spiro monodentate and bidentate phosphorous ligands have been successfully used in various asymmetric carbon-carbon bond-forming reactions. In addition, to meet the growing demands for green chemistry, the lab is working to develop new catalytic transformations that convert raw materials into valuable products in an atom-economical manner.

n Rh(I)-ShiP complexes catalyzed asymmetric arylation of aldehydes, ketones and imines

n Rh(I)-SDP complexes catalyzed hydrosilylation/cyclization of alkenes

n Pd(0)-ShiP complexes catalyzed allylation of aldehydes and ketones

n Ni(0)-SITCP complexes catalyzed three-component coupling reaction

n Ni(0)-SIPHOS complexes catalyzed hydrovinylation of alkenes

n Ni(0)-PCy₃ complexes catalyzed hydroacylation of alkenes with aldehydes

n Ni(0)-SpiroAP complexes catalyzed asymmetric hydroarylation of alkenes

n Ni(0)-HO-BIPHEP complexes catalyzed hydroalkylation of dienes with ketones